Dr. Cox's (John C. McGinley) hospital romance with medical student Kristin (Kelli Williams) continues to heat up. They are even holding hands in public. But things get derailed when their special evening is postponed due to a situation that Dr. Cox has to attend to. His situation is helping Carla (Judy Reyes) pick-up a dresser after work. After he returns home, Cox listens to the enticing message that Kristin left for him. He later gets a startling jolt when his ex-wife Jordan (Christa Miller) suddenly appears in his apartment. She has shown up for one of their post-divorce booty calls. He explains to her that he's torn between two women, Kristin, who is completely available, and Carla, who is completely unavailable. But despite his dilemma, he and Jordan have sex anyway. Things go from bad to worse when Jordan and Kristin meet in the cafeteria and then Carla stops by to thank him for helping to pick-up the dresser. Kristin gets upset because she realizes that's why he blew off their date. Then Cox puts his foot in his mouth when he alludes to the fact that he and Jordan were together the night before. Kristin ends their relationship immediately. But old habits are hard to break, Cox and Jordan resume their sexual activities a few days later.

Elliot (Sarah Chalke) meanwhile, is obsessed with an old song that may or may not be the voice of Dr. Kelso (Ken Jenkins). J.D. (Zach Braff) is upset because of how he treated a patient that he and Carla had, Mr. Simon (Jack Shearer). The patient was very mean and rude. He died a few days later. J.D. thinks his treatment of Mr. Simon may have contributed to his death. J.D. becomes even more nervous when he is called to present Mr. Simon's case to the Morbidity and Mortality conference. Although his treatment of the patient was found to be in order, J.D. reevaluates how he treats people. Particularly how he treats patient Jerry Donovan, aka J.D. #1 (Eric Saiet), who is mentally handicapped. J.D. realizes that he needs to treat everyone with compassion and professionalism, whether they are nice folks or not.